To evaluate the anti ulcer activity of leaf extract of conzya canadensis using experimental model and to asses its potential as a natural therapeutic agent and gastric ulcer

Abstract

Conyza canadensis (L.) Cronquist, commonly known as Horseweed or Canadian fleabane, is an annual herb belonging to the family Asteraceae. Native to North America, it is widely distributed in Canada and other temperate regions. Traditionally, the plant has been valued for its astringent, diuretic, and anti-inflammatory properties quercetin anti-ulcer activitry and invitro study murine macrophage cell line. The present study aimed to evaluate the anti-ulcer activity of Conyza canadensis, with a particular focus on its bioactive constituents such as limonene, flavonoids, polyphenols, and quercetin.[1] Indigenous peoples used it for the treatment of diarrhoea, dysentery, internal bleeding, fever, and urinary tract disorders. The aerial parts contain flavonoids, tannins, and essential oils (such as limonene and linalool), which contribute to its medicinal actions. Modern phytochemical investigations indicate potential antimicrobial, antioxidant, and anti-inflammatory effects, supporting some of its traditional uses. Although generally considered safe in small therapeutic doses, its efficacy and safety require further pharmacological and toxicological studies. Overall, Conyza canadensis represents a promising herbal resource with diverse traditional applications and emerging scientific relevance.